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  • Heparin as a treatment for COVID-19

  • Spike glycoprotein (S)

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SARS-CoV-2 S Protein May Have Multiple Heparin Binding Sites

Partridge et al. have observed multiple heparin binding sites on the SARS-CoV-2 S protein, including:

  • one at the furin cleavage site between the S1 and S2 subunits
  • others in the S2 domain
  • others in the receptor binding domain (RBD)

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1

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Updated 2020-07-22

Contributors are:

BK
Ben Kessler
🏆 2

Who are from:

MS
Michigan State University
🏆 2

References


  • ACE2-independent interaction of SARS-CoV-2 spike protein to human epithelial cells can be inhibited by unfractionated heparin

Tags

SARS-CoV-2 (COVID-19)

Biomedical Sciences

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