Infections of Zika are characterized by cell death and dys-mitosis of neuroepithelial stem cells. The vector which transmits Zika is the Aedes species of mosquitoes. 

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- Pathogenesis/Vector
- Presentation of Maternal Infection
- Diagnosis
- Fetal/Neonatal Abnormalities
- Vaccines

Zika Virus

First isolated in the Zika forest in Uganda, this virus is spread primarily by mosquitos in tropical and subtropical climates.

Nausheen, F., S. Bashir, S., &amp; N. Atapattu, D. (2018). Pregnancy associated arbovirus infections. Clinical Microbiology and Infectious Diseases, 3(2). https://doi.org/10.15761/cmid.1000138 

Pregnancy Associated Arbovirus Infections

Diagnosis of Zika infections include:
- RT-PCR tests
- IgM and plaque reduction neutralization tests

Diagnosing Zika Virus 

Maternal infections are characterized by the presence of any of the following:
- fever
- rash
- arthralgia
- conjunctivitis
- Guillain-Barre Syndrome
- meningoencephalitis

Maternal Zika Virus Infection Presentation

Indications of Zika infections in fetuses include microcephaly and the congenital Zika syndrome. 

Fetal/Neonatal Anomalies with Zika Virus

There are no commercially available vaccines for Zika. 

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