Cytokines produce inflammatory conditions that caused joint and tissue damage. The proliferation of osteoclasts produce bone erosion. The Aedes species of mosquitoes are the vectors for this disease. 

Tulane University

Georgetown University

- Pathogenesis/Vector
- Presentation of Maternal Infection
- Diagnosis
- Fetal/Neonatal Abnormalities
- Vaccines

Chikungunya

Discovered in east Africa, Chikungunya virus is spread by mosquitoes across Asia and South America as well, causing a flu like illness.

Chikungunya virus (CHIKV)

Nausheen, F., S. Bashir, S., &amp; N. Atapattu, D. (2018). Pregnancy associated arbovirus infections. Clinical Microbiology and Infectious Diseases, 3(2). https://doi.org/10.15761/cmid.1000138 

Pregnancy Associated Arbovirus Infections

Clinical manifestations of Chikungunya in pregnant women include fever, headache, rash, photophobia, bone density alterations and chronic bone and joint disease. 

Maternal Chikungunya Infection Presentation

Fetal abnormalities include congenital malformations, still births, uterine growth retardation and fetal heart defects. 

Fetal/Neonatal Anomalies from Chikungunya

No available vaccines exist for Chikungunya

Vaccines for Chikungunya

IgM/IgG-ELISA and reverse transcription polymerase chain reaction (RT-PCR) diagnostic tests are used to detect Chikungunya virus (CHIKV) infections.

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